Recombinant Human IL-3 Protein
Recombinant Human IL-3 Protein
- Stock: In Stock
- Model: GMP-TL511
$134.00
Available Options
Activated T cells generally
cannot survive for a long time in vitro culture, and the addition of IL-2 can
promote their long-term and sustained proliferation. The surface of stationary
T cells does not express IL-2R and does not respond to IL-2; T cells activated
by mitogen or other stimuli can express IL-2R and become target cells of IL-2;
IL-2 can also induce increased IL-2R expression in target cells. The expression
of IL-2R on T cells is transient, generally reaching its peak 2-3 days after
activation and disappearing around 6-10 days. With the disappearance of IL-2R,
T cells lose their ability to respond to IL-2. Therefore, in order to maintain
the long-term growth of normal T cells in vitro, it is necessary to constantly
stimulate T cells with mitogen or other stimulators to maintain the expression
of IL-2R. NK cells are the only lymphoid cells that normally express IL-2R, and
therefore always maintain reactivity to IL-2. However, only IL-2R is expressed
on stationary NK cells β Chain and γ Chains have a low affinity for IL-2 and
can only react with high concentrations of IL-2. Once NK cells are activated,
they express IL-2R α Chain, becoming a high affinity receptor.
Cytokines | |
Expression Host | A DNA sequence encoding the human IL-3 (GenBank: AAA59146.1) was expressed with a His-tag at the C-terminus. |
Synonym | StabilityStabilityStabilityStability |
Protein Sequence | Protein SequenceProtein Sequence |
Molecular Mass | Molecular MassMolecular Mass |
QC Testing Purity | QC Testing PurityQC Testing Purity |
Endotoxin | MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor |
Activity | HEK293 cells |
Formulation | The recombinant human IL-3 protein consists of 139 amino acids and predicts a molecular mass of 15.9 kD. |
Stability | StabilityStabilityStabilityStability |
Storage | StorageStorageStorage |
Thumb | File information |
GMP-TL511_Product Sheet.pdf File Size80.66KB Downloaded: 87 | |
GMP-TL511_SDS.pdf File Size161.55KB Downloaded: 101 |