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Anti-Human CD52 mAb

Anti-Human CD52 mAb
Anti-Human CD52 mAb
  • Stock: In Stock
  • Model: GMP-TL112
$101.00

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CD52 is a widely distributed antigen belonging to a GPI anchored glycoprotein with only twelve amino acid residues (GQNDTSQTSSPS). CD52 can be found on the surface of lymphocytes, monocytes,eosophils and dendritic cells in hematopoietic system. with a density of up to 5×10⁵molecules on lymphocytes, CD52 antigens express on many lymphoid cell malignancies and certain acute myeloid leukemia cells. When CD52 molecules are crosslinked with mAb, it triggers a series of signaling within the target cells.The signaling caused by the activation of CD52 molecules is similar to that caused by anti-CD3 antibodies. When CD52 molecules are triggered, PMA (Phorbol Myristate acetate, acetylmyridrobol ester) can promote the proliferation and secretion of cytokines in normal human CD4⁺and CD8⁺Tlymphocytes in vitro.

Cytokines
Expression Host HEK293 cells
QC Testing Purity > 90 % as determined by SDS-PAGE.
Endotoxin < 0.1EU per μg of the protein as determined by the LAL method.
Activity The binding rate with MC/CAR
Formulation Supplied as a 0.22μm filtered solution in PBS, PH 7.4.
Stability 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.
Storage 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.
Thumb File information
GMP-TL112_SDS.pdf 93.13KB 80
GMP-TL112_Product Sheet.pdf 78.96KB 100

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