Anti-Human CD52 mAb
- Stock: In Stock
- Model: GMP-TL112
Available Options
CD52 is a widely distributed antigen belonging to a GPI anchored glycoprotein with only twelve amino acid residues (GQNDTSQTSSPS). CD52 can be found on the surface of lymphocytes, monocytes,eosophils and dendritic cells in hematopoietic system. with a density of up to 5×10⁵molecules on lymphocytes, CD52 antigens express on many lymphoid cell malignancies and certain acute myeloid leukemia cells. When CD52 molecules are crosslinked with mAb, it triggers a series of signaling within the target cells.The signaling caused by the activation of CD52 molecules is similar to that caused by anti-CD3 antibodies. When CD52 molecules are triggered, PMA (Phorbol Myristate acetate, acetylmyridrobol ester) can promote the proliferation and secretion of cytokines in normal human CD4⁺and CD8⁺Tlymphocytes in vitro.
Cytokines | |
Expression Host | HEK293 cells |
QC Testing Purity | > 90 % as determined by SDS-PAGE. |
Endotoxin | < 0.1EU per μg of the protein as determined by the LAL method. |
Activity | The binding rate with MC/CAR |
Formulation | Supplied as a 0.22μm filtered solution in PBS, PH 7.4. |
Stability | 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles. |
Storage | 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles. |
Thumb | File information |
GMP-TL112_SDS.pdf File Size93.13KB Downloaded: 80 | |
GMP-TL112_Product Sheet.pdf File Size78.96KB Downloaded: 100 |